Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank MMDB PDB Article PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay | Bioorg Med Chem 19: 243-8 (2011) Article DOI: 10.1016/j.bmc.2010.11.031 BindingDB Entry DOI: 10.7270/Q2B858D2 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Cannabinoid receptor 1 (Homo sapiens (Human)) | BDBM50172899 (3,4-diarylpyrazoline derivative | CHEMBL195050) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Displacement of radioligand CP55940 from human CB1 receptor expressed in CHO cells by radioligand binding assay | Drug Metab Dispos 39: 1294-302 (2011) Article DOI: 10.1124/dmd.110.037812 BindingDB Entry DOI: 10.7270/Q2MK6FMS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Homo sapiens (Human)) | BDBM50172900 (3,4-diarylpyrazoline derivative | CHEMBL197040) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 155 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Displacement of radioligand CP55940 from human CB1 receptor expressed in CHO cells by radioligand binding assay | Drug Metab Dispos 39: 1294-302 (2011) Article DOI: 10.1124/dmd.110.037812 BindingDB Entry DOI: 10.7270/Q2MK6FMS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM14390 (5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Displacement of [3H]ZM241385 from human AA2AR expressed in HEK293T cells after 2 hrs by liquid scintillation counter | J Med Chem 55: 5311-25 (2012) Article DOI: 10.1021/jm300280e BindingDB Entry DOI: 10.7270/Q2N58NFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Homo sapiens (Human)) | BDBM50172909 (3,4-diarylpyrazoline derivative | CHEMBL372650) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 223 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Displacement of radioligand CP55940 from human CB1 receptor expressed in CHO cells by radioligand binding assay | Drug Metab Dispos 39: 1294-302 (2011) Article DOI: 10.1124/dmd.110.037812 BindingDB Entry DOI: 10.7270/Q2MK6FMS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Homo sapiens (Human)) | BDBM50172904 (3,4-diarylpyrazoline derivative | CHEMBL196989) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 231 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Displacement of radioligand CP55940 from human CB1 receptor expressed in CHO cells by radioligand binding assay | Drug Metab Dispos 39: 1294-302 (2011) Article DOI: 10.1124/dmd.110.037812 BindingDB Entry DOI: 10.7270/Q2MK6FMS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | 250 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay | Bioorg Med Chem 19: 243-8 (2011) Article DOI: 10.1016/j.bmc.2010.11.031 BindingDB Entry DOI: 10.7270/Q2B858D2 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM50333132 (CHEMBL1644701 | sodium iminodisulfate) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem | Article PubMed | 310 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay | Bioorg Med Chem 19: 243-8 (2011) Article DOI: 10.1016/j.bmc.2010.11.031 BindingDB Entry DOI: 10.7270/Q2B858D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM50389841 (CHEMBL2070717) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | 631 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Displacement of [3H]ZM241385 from human AA2AR expressed in HEK293T cells after 2 hrs by liquid scintillation counter | J Med Chem 55: 5311-25 (2012) Article DOI: 10.1021/jm300280e BindingDB Entry DOI: 10.7270/Q2N58NFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM50389831 (CHEMBL2070727) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 631 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Displacement of [3H]ZM241385 from human AA2AR expressed in HEK293T cells after 2 hrs by liquid scintillation counter | J Med Chem 55: 5311-25 (2012) Article DOI: 10.1021/jm300280e BindingDB Entry DOI: 10.7270/Q2N58NFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50333132 (CHEMBL1644701 | sodium iminodisulfate) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem | Article PubMed | 760 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay | Bioorg Med Chem 19: 243-8 (2011) Article DOI: 10.1016/j.bmc.2010.11.031 BindingDB Entry DOI: 10.7270/Q2B858D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM50010231 (CHEMBL107217 | Ditiocarb sodium | Sodium salt of D...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 790 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay | Bioorg Med Chem 19: 243-8 (2011) Article DOI: 10.1016/j.bmc.2010.11.031 BindingDB Entry DOI: 10.7270/Q2B858D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-2 adrenergic receptor (Homo sapiens (Human)) | BDBM50389828 (CHEMBL2070834) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 794 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Displacement of [3H]dihydroalprenolol from human ADRB2 expressed in HEK293T cells after 1 hr by liquid scintillation counter | J Med Chem 55: 5311-25 (2012) Article DOI: 10.1021/jm300280e BindingDB Entry DOI: 10.7270/Q2N58NFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM44650 (1-({6-[(cyanomethyl)thio]benzimidazo[1,2-c]quinazo...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Displacement of [3H]ZM241385 from human AA2AR expressed in HEK293T cells after 2 hrs by liquid scintillation counter | J Med Chem 55: 5311-25 (2012) Article DOI: 10.1021/jm300280e BindingDB Entry DOI: 10.7270/Q2N58NFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM50389839 (CHEMBL2070719) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Displacement of [3H]ZM241385 from human AA2AR expressed in HEK293T cells after 2 hrs by liquid scintillation counter | J Med Chem 55: 5311-25 (2012) Article DOI: 10.1021/jm300280e BindingDB Entry DOI: 10.7270/Q2N58NFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM51080 (4-[(2Z)-2-(2-oxo-1-naphthalenylidene)hydrazinyl]-1...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Displacement of [3H]ZM241385 from human AA2AR expressed in HEK293T cells after 2 hrs by liquid scintillation counter | J Med Chem 55: 5311-25 (2012) Article DOI: 10.1021/jm300280e BindingDB Entry DOI: 10.7270/Q2N58NFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Multidrug resistance-associated protein 1 (Homo sapiens (Human)) | BDBM21278 (5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Noncompetitive inhibition of MRP1-mediated E2-17betaG transport in human MRP1 expressing HEK293 cells by Dixon plot | Drug Metab Dispos 39: 1294-302 (2011) Article DOI: 10.1124/dmd.110.037812 BindingDB Entry DOI: 10.7270/Q2MK6FMS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM50389837 (CHEMBL2070721) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.59E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Displacement of [3H]ZM241385 from human AA2AR expressed in HEK293T cells after 2 hrs by liquid scintillation counter | J Med Chem 55: 5311-25 (2012) Article DOI: 10.1021/jm300280e BindingDB Entry DOI: 10.7270/Q2N58NFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM50389846 (CHEMBL2070720) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.59E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Displacement of [3H]ZM241385 from human AA2AR expressed in HEK293T cells after 2 hrs by liquid scintillation counter | J Med Chem 55: 5311-25 (2012) Article DOI: 10.1021/jm300280e BindingDB Entry DOI: 10.7270/Q2N58NFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-2 adrenergic receptor (Homo sapiens (Human)) | BDBM50389827 (CHEMBL1907082) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Displacement of [3H]dihydroalprenolol from human ADRB2 expressed in HEK293T cells after 1 hr by liquid scintillation counter | J Med Chem 55: 5311-25 (2012) Article DOI: 10.1021/jm300280e BindingDB Entry DOI: 10.7270/Q2N58NFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM50389832 (CHEMBL2070726) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 2.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Displacement of [3H]ZM241385 from human AA2AR expressed in HEK293T cells after 2 hrs by liquid scintillation counter | J Med Chem 55: 5311-25 (2012) Article DOI: 10.1021/jm300280e BindingDB Entry DOI: 10.7270/Q2N58NFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM50389834 (CHEMBL2070725) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | 2.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Displacement of [3H]ZM241385 from human AA2AR expressed in HEK293T cells after 2 hrs by liquid scintillation counter | J Med Chem 55: 5311-25 (2012) Article DOI: 10.1021/jm300280e BindingDB Entry DOI: 10.7270/Q2N58NFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50010231 (CHEMBL107217 | Ditiocarb sodium | Sodium salt of D...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 3.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay | Bioorg Med Chem 19: 243-8 (2011) Article DOI: 10.1016/j.bmc.2010.11.031 BindingDB Entry DOI: 10.7270/Q2B858D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM50389835 (CHEMBL2070724) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | 3.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Displacement of [3H]ZM241385 from human AA2AR expressed in HEK293T cells after 2 hrs by liquid scintillation counter | J Med Chem 55: 5311-25 (2012) Article DOI: 10.1021/jm300280e BindingDB Entry DOI: 10.7270/Q2N58NFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM50389845 (CHEMBL1362986) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 3.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Displacement of [3H]ZM241385 from human AA2AR expressed in HEK293T cells after 2 hrs by liquid scintillation counter | J Med Chem 55: 5311-25 (2012) Article DOI: 10.1021/jm300280e BindingDB Entry DOI: 10.7270/Q2N58NFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-binding cassette sub-family C member 4 (Homo sapiens (Human)) | BDBM21278 (5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Noncompetitive inhibition of MRP4-mediated E2-17betaG transport in human MRP4 expressing HEK293 cells by Dixon plot | Drug Metab Dispos 39: 1294-302 (2011) Article DOI: 10.1124/dmd.110.037812 BindingDB Entry DOI: 10.7270/Q2MK6FMS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM50389833 (CHEMBL1089322) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Displacement of [3H]ZM241385 from human AA2AR expressed in HEK293T cells after 2 hrs by liquid scintillation counter | J Med Chem 55: 5311-25 (2012) Article DOI: 10.1021/jm300280e BindingDB Entry DOI: 10.7270/Q2N58NFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM50389844 (CHEMBL2070728) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 5.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Displacement of [3H]ZM241385 from human AA2AR expressed in HEK293T cells after 2 hrs by liquid scintillation counter | J Med Chem 55: 5311-25 (2012) Article DOI: 10.1021/jm300280e BindingDB Entry DOI: 10.7270/Q2N58NFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM50389829 (CHEMBL2070833) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | 5.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Displacement of [3H]ZM241385 from human AA2AR expressed in HEK293T cells after 2 hrs by liquid scintillation counter | J Med Chem 55: 5311-25 (2012) Article DOI: 10.1021/jm300280e BindingDB Entry DOI: 10.7270/Q2N58NFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM50389830 (CHEMBL1714515) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | 5.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Displacement of [3H]ZM241385 from human AA2AR expressed in HEK293T cells after 2 hrs by liquid scintillation counter | J Med Chem 55: 5311-25 (2012) Article DOI: 10.1021/jm300280e BindingDB Entry DOI: 10.7270/Q2N58NFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM50389836 (CHEMBL2070722) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 5.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Displacement of [3H]ZM241385 from human AA2AR expressed in HEK293T cells after 2 hrs by liquid scintillation counter | J Med Chem 55: 5311-25 (2012) Article DOI: 10.1021/jm300280e BindingDB Entry DOI: 10.7270/Q2N58NFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM50389842 (CHEMBL2070723) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 6.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Displacement of [3H]ZM241385 from human AA2AR expressed in HEK293T cells after 2 hrs by liquid scintillation counter | J Med Chem 55: 5311-25 (2012) Article DOI: 10.1021/jm300280e BindingDB Entry DOI: 10.7270/Q2N58NFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-binding cassette sub-family C member 4 (Homo sapiens (Human)) | BDBM50172903 (3,4-diarylpyrazoline derivative | CHEMBL364300) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Noncompetitive inhibition of MRP4-mediated E2-17betaG transport in human MRP4 expressing HEK293 cells by Dixon plot | Drug Metab Dispos 39: 1294-302 (2011) Article DOI: 10.1124/dmd.110.037812 BindingDB Entry DOI: 10.7270/Q2MK6FMS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM50278323 (CHEMBL471245 | sodium trithiocarbonate) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 8.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay | Bioorg Med Chem 19: 243-8 (2011) Article DOI: 10.1016/j.bmc.2010.11.031 BindingDB Entry DOI: 10.7270/Q2B858D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50278323 (CHEMBL471245 | sodium trithiocarbonate) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 8.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay | Bioorg Med Chem 19: 243-8 (2011) Article DOI: 10.1016/j.bmc.2010.11.031 BindingDB Entry DOI: 10.7270/Q2B858D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase (Methanobacterium thermoautotrophicum) | BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 1.21E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Inhibition of Methanothermobacter thermautotrophicus carbonic anhydrase after 15 mins by stopped flow CO2 hydration assay | Bioorg Med Chem 19: 243-8 (2011) Article DOI: 10.1016/j.bmc.2010.11.031 BindingDB Entry DOI: 10.7270/Q2B858D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-2 adrenergic receptor (Homo sapiens (Human)) | BDBM50389824 (CHEMBL2070835) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.51E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Displacement of [3H]dihydroalprenolol from human ADRB2 expressed in HEK293T cells after 1 hr by liquid scintillation counter | J Med Chem 55: 5311-25 (2012) Article DOI: 10.1021/jm300280e BindingDB Entry DOI: 10.7270/Q2N58NFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-2 adrenergic receptor (Homo sapiens (Human)) | BDBM50389843 (CHEMBL1622248) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | 3.98E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Displacement of [3H]dihydroalprenolol from human ADRB2 expressed in HEK293T cells after 1 hr by liquid scintillation counter | J Med Chem 55: 5311-25 (2012) Article DOI: 10.1021/jm300280e BindingDB Entry DOI: 10.7270/Q2N58NFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-2 adrenergic receptor (Homo sapiens (Human)) | BDBM50389826 (CHEMBL1620339) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.98E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Displacement of [3H]dihydroalprenolol from human ADRB2 expressed in HEK293T cells after 1 hr by liquid scintillation counter | J Med Chem 55: 5311-25 (2012) Article DOI: 10.1021/jm300280e BindingDB Entry DOI: 10.7270/Q2N58NFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50278319 (CHEMBL502764 | sodium persulfate) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem | Article PubMed | 8.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay | Bioorg Med Chem 19: 243-8 (2011) Article DOI: 10.1016/j.bmc.2010.11.031 BindingDB Entry DOI: 10.7270/Q2B858D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM50278320 (CHEMBL2069541 | CHEMBL448089 | sodium selenocyanat...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 8.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay | Bioorg Med Chem 19: 243-8 (2011) Article DOI: 10.1016/j.bmc.2010.11.031 BindingDB Entry DOI: 10.7270/Q2B858D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50278320 (CHEMBL2069541 | CHEMBL448089 | sodium selenocyanat...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 8.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay | Bioorg Med Chem 19: 243-8 (2011) Article DOI: 10.1016/j.bmc.2010.11.031 BindingDB Entry DOI: 10.7270/Q2B858D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM50278319 (CHEMBL502764 | sodium persulfate) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem | Article PubMed | 1.07E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay | Bioorg Med Chem 19: 243-8 (2011) Article DOI: 10.1016/j.bmc.2010.11.031 BindingDB Entry DOI: 10.7270/Q2B858D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM50278318 (CHEMBL444819 | sodium perrhenate(VII)) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem | Article PubMed | 1.10E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay | Bioorg Med Chem 19: 243-8 (2011) Article DOI: 10.1016/j.bmc.2010.11.031 BindingDB Entry DOI: 10.7270/Q2B858D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50278322 (CHEMBL450253 | sodium fluorosulfate) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents | Article PubMed | 4.60E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay | Bioorg Med Chem 19: 243-8 (2011) Article DOI: 10.1016/j.bmc.2010.11.031 BindingDB Entry DOI: 10.7270/Q2B858D2 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM50333131 (CHEMBL1075630 | sodium pyrovanadate(V) | tetrasodi...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.40E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay | Bioorg Med Chem 19: 243-8 (2011) Article DOI: 10.1016/j.bmc.2010.11.031 BindingDB Entry DOI: 10.7270/Q2B858D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50333131 (CHEMBL1075630 | sodium pyrovanadate(V) | tetrasodi...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay | Bioorg Med Chem 19: 243-8 (2011) Article DOI: 10.1016/j.bmc.2010.11.031 BindingDB Entry DOI: 10.7270/Q2B858D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM50278312 (CHEMBL445433 | sodium stannate(IV)) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | 5.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay | Bioorg Med Chem 19: 243-8 (2011) Article DOI: 10.1016/j.bmc.2010.11.031 BindingDB Entry DOI: 10.7270/Q2B858D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM50278313 (CHEMBL471869 | sodium tellurate(VI)) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | 6.60E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay | Bioorg Med Chem 19: 243-8 (2011) Article DOI: 10.1016/j.bmc.2010.11.031 BindingDB Entry DOI: 10.7270/Q2B858D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50278318 (CHEMBL444819 | sodium perrhenate(VII)) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem | Article PubMed | 7.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay | Bioorg Med Chem 19: 243-8 (2011) Article DOI: 10.1016/j.bmc.2010.11.031 BindingDB Entry DOI: 10.7270/Q2B858D2 | |||||||||||
More data for this Ligand-Target Pair |
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